[Comparison between magnesium sulfate and dexmedetomidine in controlled hypotension during functional endoscopic sinus surgery].
نویسندگان
چکیده
BACKGROUND AND OBJECTIVES It is crucial to decrease bleeding during functional endoscopic sinus surgery. Our primary goal was to investigate the effects of magnesium sulfate and dexmedetomidine used for controlled hypotension on the visibility of the surgical site. METHODS 60 patients aged between 18 and 65 years were enrolled. In the magnesium sulfate group (Group M), patients were administered 40mg/kg magnesium sulfate in 100mL saline solution over 10min as the intravenous loading dose 10min before induction, with a subsequent 10-15mg/kg/h infusion during surgery. In the dexmedetomidine group (Group D), patients were administered 1μg/kg dexmedetomidine in 100mL saline solution as the loading dose 10min before surgery and 0.5-1μg/kg/h dexmedetomidine during surgery. Deliberate hypotension was defined as a mean arterial pressure of 60-70mmHg. RESULTS Bleeding score was significantly decreased in Group D (p=0.002). Mean arterial pressure values were significantly decreased in Group D compared to that in Group M, except for the initial stage, after induction and 5min after intubation (p<0.05). The number of patients who required nitroglycerine was significantly lower in Group D (p=0.01) and surgeon satisfaction was significantly increased in the same group (p=0.001). Aldrete recovery score ≥9 duration was significantly shorter in Group D (p=0.001). There was no difference between the two groups in terms of recovery room verbal numerical rating scale. CONCLUSIONS Dexmedetomidine can provide more effective controlled hypotension and thus contribute to improved visibility of the surgical site.
منابع مشابه
مقایسه اﺛﺮ ﺳﻮﻟﻔﺎت ﻣﻨﯿﺰیوم و دﮐﺴﻤﺪﺗﻮﻣﯿﺪین ﺑﺮ ﮐﯿﻔﯿﺖ ﻓﯿﻠﺪ ﺟﺮاﺣﯽ در ﺑﯿﻤﺎران ﮐﺎﻧﺪید ﻋﻤﻞ جراحی اﻧﺪوﺳﮑﻮﭘﯿﮏ ﺳﯿﻨﻮس
Background and Objective: One of the main treatments for chronic rhinosinusitis is endoscopic surgery. In this procedure, intraoperative bleeding due to limited view of the surgeon can bring about surgical complications. To have a clear operation field for endoscopic sinus surgery, bleeding management is necessary. We aimed to compare the effects of magnesium sulfate and dexmedetomidine on oper...
متن کامل[Comparison of the effects of magnesium sulphate and dexmedetomidine on surgical vision quality in endoscopic sinus surgery: randomized clinical study].
BACKGROUND AND OBJECTIVES Even a small amount of bleeding during endoscopic sinus surgery can corrupt the endoscopic field and complicate the procedure. Various techniques, including induced hypotension, can minimize bleeding during endoscopic sinus surgery. The aim of this study was to compare the surgical vision quality, haemodynamic parameters, postoperative pain, and other effects of magnes...
متن کاملComparison of Dexmedetomidine-Isoflurane versus Fentanyl-Propofol based anesthesia for controlled hypotension in functional endoscopic sinus surgery
متن کامل
Dexmedetomidine Efficacy in Quality of Surgical Field During Endoscopic Sinus Surgery
Introduction: Blood loss is a common concern during functional endoscopic sinus surgery (FESS). The present study aimed to evaluate the efficacy of dexmedetomidine (DEX) in intraoperative bleeding and surgical field in FESS. Materials and Methods: This double-blind randomized clinical trial was conducted on 72 patients within the age range of 16-60 years who underwent ...
متن کاملComparison of the Effects of Dexmedetomidine and Labetalol on Controlled Hypotension in Maxillofacial Surgery
Background & objectives: The use of controlled hypotension is important to reduce bleeding in some surgeries. This study aimed to determine the effects of dexmedetomidine (DEX) and labetalol for induced hypotension in maxillofacial fractures surgery. Methods: In this triple-blind randomized controlled clinical trial study, the patients with maxillofacial fractures were randomly divided into two...
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عنوان ژورنال:
- Revista brasileira de anestesiologia
دوره 65 1 شماره
صفحات -
تاریخ انتشار 2015